PRINCIPAL CONSULTING TOXICOLOGIST
EDUCATION AND CERTIFICATIONS
1973 — Ph.D., in Pathology, University of Texas Health Science Center at Houston, TX
Dissertation Title: Copper-Binding Proteins in Normal Human Serum and in Hodgkin’s Disease
1971 — M.S., in Pathology, University of Texas Health Science Center at Houston, TX
Thesis Title: Serum Copper Relation to Estrogen Administration: A Comparative Study
1969 — B.S., Biology, Tulane University, New Orleans, LA.
2006-Present – Consulting Toxicologist, Houston, Texas
2003-2006 – Exponent: Houston, Texas
2003 – Present Principal and Vice President, RAM Group; Houston, Texas
1996 – Present Adjunct Professor (Toxicology/Risk Assessment), University of Texas Health Science Center at Houston
2001 – 2003 Senior Scientist, Conestoga-Rovers & Associates, Houston, Texas
1999 – 2001 Principal and Vice President, RAM Group; Houston, Texas
1995-1999 Principal and Executive Vice President; Compliance Solutions, Inc.; Houston, Texas
1993 – 1995 Principal/Senior Science Advisor; ENVIRON Corporation; Houston, Texas
1990 – 1993 Regional Program Manager/Director of Toxicology and Risk Management; ENSR Consulting & Engineering; Houston, Texas
1977 – 1990 Staff Toxicologist; Shell Oil Company, Health, Safety & Environment, Houston, Texas.
Toxicologist, Shell Oil Company. Provided primary toxicological support for a wide range of product/process areas including petroleum exploration and production, refinery operations, gasoline, kerosene, diesel fuels, lubricants, asphalts, aromatics, olefins, solvents, metals, catalysts, radiation, and synfuels.
Chairman, American Petroleum Institute’s (API) Toxicology Committee, which was responsible for the design, contracting, monitoring, and interpretation of a wide range of industry-sponsored research programs on various chemicals and complex mixtures derived from petroleum. The committee also provided technical support to other API groups for use in issue and regulatory responses.
Chairman, API Benzene Toxicology (PS-7) Task Force for more than 10 years. He was a major contributor to the design and direction of API’s interdisciplinary research program on this compound.
Chairman, API Neurotoxicity Task Force (PS-29) which evaluated the toxicity of n-hexane and other solvents to the nervous system.
Chairman, Toxicology Research Task Group of the Chemical Manufacturers Association’s (CMA) Butadiene Program Panel, and a major contributor to the development of regulatory and litigation strategies for this compound.
North American representative to the Butadiene Steering Committee of the International Institute of Synthetic Rubber Producers (IISRP), which developed international strategies for the Synthetic Rubber Industry with regard to butadiene health concerns.
Risk Assessment and Regulatory Negotiation
Project Manager for health risk-based prioritization of 48 waste management areas (including identification of media and chemicals of concern) at a major chemical plant in Texas. This was part of a proactive regulatory strategy which allowed the client to maintain control of how and where its technical and financial resources would be spent at the plant.
Managed the development of the Baseline Risk Assessment for the Waite Park Superfund Site.
Invited by both the Texas Water Commission and the Texas Chemical Council to review the development of the State’s Risk Reduction Rules for expediting the voluntary remediation/cleanup of contaminated sites.
Principal-in-Charge for developing risk-based target cleanup concentrations at a pesticide formulation plant in Texas. Demonstrated that according to draft state guidelines, only certain areas of surface soil would require remedial attention (approximately 15% of the soil volume proposed by previous consultant). Demonstrated that no remedial activities or post-closure care would be required for subsurface soils, ground water, or surface water.
Principal-in-Charge for a project which initially was intended to utilize risk assessment to close a large impoundment basin at a petrochemical complex — a key step of a large wastewater management program. During the data analysis stage, it was concluded that the proposed risk-based closure of a impoundment basin was unnecessary because of alternative regulatory guidance and that the health risks associated with the existing basin were negligible. Approximate client savings were $17 million.
Managed project evaluating whether chemical substances found in the soils at a former foundry were at concentrations that would preclude multi-million dollar sale of the property for an apartment development in Texas. Innovative statistical analysis of available analytical data established that the chemical concentrations were consistent with site- specific background concentrations, and that the conditions at the facility would meet the TNRCC Risk Reduction Rule guidelines for residential land use. The results of this evaluation were presented to senior TNRCC staff who subsequently issued a letter to the client concurring with the conclusions of the analysis.
Managed risk assessment task seeking to close a borrow pit containing metal-based catalysts and various organic chemicals. Using the TNRCC Risk Reduction Rules, it was demonstrated that current conditions justified closing the borrow pit without remedial action. Approximate savings to client were $9 million.
Developed three-day course at request of the Secretary of the Louisiana Department of Environmental Quality to familiarize DEQ staff with the comprehensive risk assessment procedures being considered for hazardous waste combustion facilities.
Principal-in-Charge for risk assessment of subdivision built above former crude oil storage pits constructed in the 1920s. The Railroad Commission of Texas has asked for an unbiased, scientifically credible assessment of the data collected by various parties involved in litigation.
Developed multi-attribute decision analytical procedure to assist a major natural gas pipeline company to prioritize the environmental concerns associated with approximately 600 stations where mercury-containing meters had previously been utilized. This form of decision analysis allowed the client’s staff to identify the specific factors that were important in establishing priorities and to define how important each of those factors were in that decision. Importantly, the procedure quickly determined where individuals differed substantially in their understanding and/or opinions so that dialogue could be established to minimize future disagreements.
Dr. Thomas has served as an Associate Member of the Environmental Litigation Associates, Houston, Texas, and
Lecturer: The Institute of Environmental Technology, 1992-1996.
PUBLICATIONS AND PRESENTATIONS
Pienta, R.J., C.F. Tessmer, and F.B. Thomas. 1969. Effect of murine oncogenic viruses on serum copper levels. Cancer Res. 10:69 (Abstract).
Thomas, F.B. 1971. Serum copper relation to estrogen administration: A comparative study. Master’s Thesis, The University of Texas Health Science Center at Houston, The Graduate School of Biomedical Sciences.
Tessmer, C.F., M. Hrgovcic, B.W. Brown, J. Wilbur, and F.B. Thomas. 1972. Serum copper correlations with bone marrow. Cancer 293-297.
Tessmer, C.F., M. Hrgovcic, F.B. Thomas, J.R. Wilbur, and D.M. Mumford. 1972. Long-term serum copper studies in acute leukemia in children. Cancer 30:358-365.
Hrgovcic, M., C.F. Tessmer, B.W. Brown, J.R. Wilbur, D.M. Mumford, F.B. Thomas, C.C. Shullenberger, and H.G. Taylor. 1973. Serum copper studies in the lymphomas and acute leukemias. In Progress in Clinical Cancer, ed. I.M. Ariel, Vol. V, 121-153. New York: Grune and Stratton.
Thomas, F.B. 1972. Atomic absorption spectrophotometry in the clinical laboratory. Proc. Annual Convention of the Texas Society of Medical Technologists, May 12, Houston, Texas.
Tessmer, C.F., M. Hrgovcic, F.B. Thomas, L.M. Fuller, and J.R. Castro. 1973. Serum copper as an index of tumor response to radiotherapy. Radiology 106-112.
Hrgovcic, M., C.F. Tessmer, F.B. Thomas, L.M. Fuller, J.F. Gamble, and C.C. Shullenberger. 1973. Significance of serum copper levels in adult patients with Hodgkin’s disease. Cancer 31:1337-1345.
Tessmer, C.F., W. Krohn, D. Johnston, F.B. Thomas, M. Hrgovcic, and B.W. Brown. 1973. Serum copper in children (6-12 years): an age correction factor. Amer. J. Clin. Path. 60:870-878.
Hrgovcic, M., C.F. Tessmer, F.B. Thomas, P.S. Ong, J.F. Gamble, and C.C. Shullenberger. 1973. Serum copper observations in patients with malignant lymphoma. Cancer 32:1512-1514.
Thomas, F.B. 1973. Copper binding proteins in normal human serum and in Hodgkin’s disease. Doctoral Dissertation, The University of Texas Health Science Center at Houston, Graduate School of Biomedical Sciences.
Thomas, F.B. 1974. Applications of Sephadex G-200 chromatography to the study of the copper binding components of human serum. Proc. Southeastern Texas Section of the American Chemical Society, Houston, Texas.
Furlong, N.B., F.B. Thomas, and C.G. Mintz. 1974. A probable mechanism for apurinic acid inhibition of DNA synthesis. FEBS Letters 41:256-258.
Tessmer, C.F., M. Hrgovcic, F.B. Thomas, J. Wilbur, and D.M. Mumford. 1974. Long-term serum copper studies in acute leukemia in children. In The Year Book of Cancer 1974, eds. R.L. Clark and R.S. Cumley. Chicago: Year Book Medical Publishers.
Mintz, C.G., F.B. Thomas, and N.B. Furlong. 1974. Approaches to the in-vitro synthesis of ara-C apurinates. Proc. Southwest Section of the American Association for Cancer Research, November 8-9, New Orleans, Louisiana.
Thomas, F.B., and N.B. Furlong. 1974. Biochemical studies on the role of DNA polymerase in benzo(a)pyrene carcinogenesis. Proc. Southwest Section of the American Association for Cancer Research, November 8-9. New Orleans, Louisiana.
Thomas, F.B., and N.B. Furlong. 1976. A simple radioassay of benzo(a)pyrene activation: Observations on the covalent interactions of benzo(a)pyrene with protein. Analytical Biochemistry 72:546-551.
Thomas, F.B., D.M. Thomas, D.S. Shewach, and N.B. Furlong. 1979. Substrate specificity of aryl hydrocarbon (benzo(a)pyrene) hydroxylase. In Proc. Polynuclear Aromatic Hydrocarbons: Third International Symposium on Chemistry and Biology–Carcinogenesis and Mutagenesis, eds. P.W. Jones and P. Leber, 669-683. Ann Arbor: Ann Arbor Science Publishers.
Lington, A.W., S.C. Lewis, F.B. Thomas, G.C. Granville, S.T. Cragg, and P.S. Spencer. 1983. The neurotoxic activity of commercial hexane mixtures in the male rat (Part I). Proc. Annual Meeting of the Society of Toxicology.
Lington, A.W., S.C. Lewis, F.B. Thomas, G.C. Granville, S.T. Cragg, and P.S. Spencer. 1983. The neurotoxic activity of commercial hexane mixtures in the male rat (Part II). Proc. Annual Meeting of the Society of Toxicology.
Thomas, F.B. 1983. Evaluation of the neurotoxic potential of hexacarbon solvent mixtures in the Sprague-Dawley rat. Invited paper, presented to the Mid-West Regional Chapter of the Society of Toxicology, May 12, Chicago, Illinois.
Thomas, F.B. 1983. Neurotoxicology. Invited paper, presented to the Deep South Section of the American Industrial Hygiene Association, October 31, New Orleans, Louisiana.
Thomas, F.B. 1984. Neurotoxicology. Invited paper, presented to the Gulf Coast Section of the American Industrial Hygiene Association, March 8, Houston, Texas.
Thomas, F.B., C.A. Halder, C.E. Holdsworth, and B.Y. Cockrell. 1984. Hydrocarbon nephropathy in male rats. Part II. Temporal and morphologic characterization of the renal lesions. In Proceedings of the Symposium on Hydrocarbon Toxicity. Surrey, England: University of Surrey.
Sussman, R.M., F.B. Thomas, and R.D. Irons. 1985. Risk assessment issues presented by 1,3-butadiene. In Risk Assessment in the Chemical Industry, 177-214. Washington, D.C.: Chemical Manufacturers Association.
Thomas, F.B. 1986. Toxicological effects of benzene. In Benzene in Florida Ground Water: An Assessment of the Significance to Human Health, 7-15. Washington, D.C.: American Petroleum Institute.
Thomas, F.B., and B.J. Simpson. 1989. Application of short-term assays by the petroleum industry to identify skin carcinogens. In Skin Carcinogenesis: Mechanisms and Human Relevance, eds. T.J. Slaga, A.J.P. Klein-Szanto, R.K. Boutwell, D.E. Stevenson, H.L. Spitzer, and B. D’Motto, 393-399, New York: Alan R. Liss.
Thomas, F.B., and M. Hulse. 1989. Compounds in asphalt cement fumes and their health effects. Invited paper, presented to the International Society for Asphalt Pavements, November 9, Baltimore, Maryland.
Von Burg, R., M. Lakin, B. Thomas, and B. Egan. 1990. Public interest group use of your SARA 313 data. Invited paper, presented at the Annual Meeting of the National Petroleum Refiners Association, March 25-27, San Antonio, Texas.
Thomas, F.B. 1990. Toxicological overview of ethylene oxide, butadiene, gasoline, polyolefin manufacturing, and composites. Invited paper, presented at the American Occupational Health Conference, May 3, Houston, Texas.
Thomas, F.B. 1990. Air toxics impacts on human health and the ecology. Presented at Air Toxic Compliance Conference, Executive Enterprises, Inc., June 11-12, Houston, Texas.
Thomas, F.B. 1990. The toxicology of 1,3-butadiene. Invited paper, presented to the American Petroleum Institute Toxicology Committee, September 2, Toronto, Ontario.
Thomas, F.B. 1990. Science vs. compliance: The argument for QA’s involvement in science. Invited paper, presented at the Annual Meeting of the Society of Quality Assurance, October 3, Orlando, Florida.
Thomas, F.B. 1990. The science and art of risk assessment. Invited paper, presented at Marathon Oil Company’s Health, Environment and Safety Conference, October 10, Houston, Texas.
Thomas, F.B. 1991. The evolving Material Safety Data Sheet. Invited paper, presented to the Dallas Bar Association, Environmental Law Section, March 28, Dallas, Texas.
Thomas, F.B. 1991. Risk assessment and the Clean Air Act Amendments. Presented at the ENSR Breakfast Seminar, May 2, Houston, Texas.
Thomas, F.B. 1991. Multi-media risk assessment. Invited paper, presented at the Bridgestone/Firestone Environmental Affairs Domestic Conference, May 8, Nashville, Tennessee.
Thomas, F.B. 1991. Application of toxicology, epidemiology and industrial hygiene. Invited paper, presented at the “Toxic Tort Litigation” Course sponsored by the Continuing Legal Education Committee of the Houston Bar Association, October 11, Houston, Texas.
Cox, L.A., Jr., and F.B. Thomas. 1992. A generic PBPK modeling tool for rapidly developing PBPK models. Toxicologist 12(1): 188 [Abstract 684].
Thomas, F.B. 1992. Multi-media risk assessment. Invited paper, presented to the Association for the Environmental Health of Soils, July, Houston, Texas.
Thomas, B., and C. Brassow. 1992. The TWC Risk Reduction Rules and remediation of soil contamination. Presented at “How to Classify and Clean up or Dispose of Solid Waste” sponsored by Texas Environmental Education Services, October 16, Houston, Texas.
Thompson, R.A., J.O. Woodrow, and F.B. Thomas. 1992. Risk based prioritization of remediation options. Presented at the Annual Meeting of the Society for Risk Analysis, December 7, San Diego, California.
Cox, L.A., Jr., F.B. Thomas, and J.O. Woodrow. 1992. Decisions with unknown consequences: A random valuation model. Presented at the Annual Meeting of the Society for Risk Analysis, December 9, San Diego, California.
Thomas B., R. Thompson, and C. Lu. 1993. The risk-based remediation of total petroleum hydrocarbon contamination of soils. Invited paper, presented at Petro-Safe ’93, January 27, Houston, Texas.
Thomas, B. 1993. Risk characterization. Invited paper, presented to the Association for the Environmental Health of Soils, May 12, Houston, Texas.
Thomas, B., L. Plunkett, and J. Wojciak. 1993. Strategic approaches to implementing the Texas Water Commission’s Risk Reduction Rules. Presented at the ENVIRON Workshop on the Risk Reduction Rules, June 17, Houston, Texas.
Leger K and B. Thomas. 1995. Managing risk creates opportunities. Amer. Oil & Gas Reporter 38(6): 100-101.
Thomas B., L. Plunkett, S.B. Libicki and W.B. Kappleman. 1995. The Comprehensive Assessment of Risks due to Emissions from Hazardous Waste Incinerators. Three-day training course prepared for the Louisiana Department of Environmental Quality, held June 26-28, 1995 in Baton Rouge, Louisiana.
Thomas B & Handley B, 1997. Risk-Based Corrective Action. Training course for the TNRCC certification of Corrective Action Project Managers. Texas Natural Resource Conservation Commission contract through the Texas A&M Engineering Extension Service.
Thomas B & Handley B, 1998. Offsite consequence analysis: the public connection. Invited paper, presented at the Hazard Assessment/Offsite Consequence Analysis Session, Petro-Safe 98, January 28, Houston, Texas.
Thomas B, 1998. Toxicological issues in the chemical processing industry. Invited paper; presented at the First Annual Symposium of the Mary Kay O’Connor Process Safety Center, George Bush Presidential Conference Center; May 30-31, College Station, Texas.
Thomas B, 1998. The toxicological significance of chemicals in water supplies (or what is clean water). Invited paper, presented at the Environmental Litigation Associates Seminar on New Ground-Water Supply Issues, April 16, Houston, Texas.
Thomas B, 1998. The toxicology of methyl tertiary-butyl ether (MTBE). Invited paper, presented at Mealey’s Underground Storage Tank Conference, June 9, Amelia Island, Florida.
Thomas B, 1999. Kekulé’s devils and E&P waste. Invited paper, presented at the Society of Petroleum Engineers – Evangeline Section, Environmental Issues Forum, February 22, Lafayette, Louisiana.
Thomas B, 1999. MTBE – toxicology and the use of animal data to prove causality. Invited paper, presented to the Second Annual Appellate Judges and Lawyers Symposium: Scientific Methodology and the Admissibility of Expert Testimony, May 13-15, The University of Kansas, Law and Organizational Economic Center, Lawrence, Kansas.
Thomas B, 1999. Evaluation of health issues associated with E&P wastes. Invited paper, presented at the Louisiana Gulf Coast Oil Exposition, October 29, Lafayette, Louisiana.
Thomas B, 1999. Toxicology of methyl tertiary-butyl ether (MTBE) – an update. Invited paper, presented at Mealey’s UST and MTBE Litigation Conference, November 16, Amelia Island, Florida.
Thomas B, 2000. A toxicologist’s perspective of MTBE. Invited paper, presented at the Petroleum Marketing Attorneys Meeting, April 4, Washington, DC.
Thomas B (2002). MTBE and benzene toxicology. Panel discussion with Scott R and Mehlman M at Mealey’s MTBE & UST Litigation Conference; November 4, Marina del Rey, California.
Feel free to contact us to discuss your project needs or to arrange a speaking engagement by one of our Associates for a professional training session, a technical conference, society meeting, or for a graduation ceremony or other function where the knowledge and experience of our Associates may be of interest to your group.